H1N1 outbreak in Japan: a recent report!

H1N1 (swine flu) outbreak was already declared an epidemic by NID (National Institute of Infectious Disease of Japan) in August. In the middle week of Aug, the average number of flu (H1N1) patients per hospital was 1.69 (1.00 or >1.00 suggests epidemic), demonstrating epidemic, exceeding the number to be about 110,000. According to August report, 3 fatalities were confirmed from H1N1. 1.00 case/week has been reported by the hospitals of 44 districts in Japan excluding Hokkaido island.
It is obligatory to use facemask in the densely populated area especially in outside and during traveling. Japan already started vaccination from middle of Oct after observing any adverse effects of vaccines; however, initially H1N1 vaccine has been reported mild headache after initial stage of vaccination in the trial and local redness at the site of injection. The winter season should be peak to spread this flu in Japan and as well other Asian countries, so special precautions must be taken.

Mystery of swine-flu (H1N1): an update.

Swine flu (H1N1 virus) has aggressive effects on humans due to its rapid replication. Though swine-flu attacks the lung parenchyma in the early phase of inflammation initiating severe lung pneumonia, recently it is studied that other vital organs (liver, kidney and brain) are brutally affected, showing its fatality. It is investigated that in the pathogenesis step inside the body, this influenza virus (swine-flu, H1N1) encourages discharge of inflammatory cytokines,
immunomodulating agents. Therefore, these inflammatory cytokines hinder liver and kidney function in the pathogenesis. Another harmful complication of swine-flu (H1N1) is, damaging of brain cells (neurons), those demonstrate irreversible. So, it is recommended to start antiflu drugs (Tamiflu or Relenza) as soon as possible with physician's prescription after H1N1 is diagnosed. It is recommended, to take temperature records regularly for the baby-care center or school-gloing children in the epidemic regions.

Is gastric ulcer linked with diabetes?

Insulin resistance diabetes is a common problem around all over the world, mainly originating from obesity due to overeating and sedentary lifestyle. Hyperglycemia is always susceptible to enhance other pathogenesis such a diabetic ulcer, angiopathy, neuropathy etc. Recently, a group of medical scientists in Japan (Tohoku University, my host University) found that one insulin resistance diabetic patient was completely recovered when treated with pylori healing antibiotic, which was published in July 18 edition of The Lancet British medical journal. The mechanism of developing insulin resistance diabetes among pylori-induced ulcer patients is not clear enough; however, there might be some autoimmune effects. We need to find out the specific immune response against insulin that causes diabetes. In another, it is not known yet whether hyperglycemia may have influence on H. pylori growth in the stomach mucosa. Therefore, it is important to treat pylori-induced stomach ulcer first in insulin-resistant diabetic patient to cure diabetes.

Virus Alert!

Influenza virus (H1N1) is spreading up all around the world especially the post-summer season will be fatal. It is said, half of the U.S citizens may be infected by this flu and 1 in 5 Japanese will be infected. At present, prevention is important for eradicate any fatality in the humans. Though some developed countries already manufactured vaccines against this flu, those are not enough. Japan intends to start supplying vaccines at the end of October only for children, older people and patients suffered from cardiac, renal or diabetes. Most of the southeast asian countries are densely populated, so, there might be a chance of having fatality due to H1N1 infection. Some important suggestions are mentioned: (1) Use of face mask especially in the densely populated area, (2) washing hands and gargle after coming home. This flu is mainly spreaded from sneeze and cough, so, during sneeze and/or cough, faces should be protected by hand or handkerchief. In another note, children, geriatric population, and people suffering from cardiac, renal or endocrine diseases, must take precautions against this flu. Finally, it is suggested that prevention of this flu is obligatory to refrain from vast fatality in the mankind.

H1N1-flu induced deaths in Japan!

Three H1N1 induced-deaths have been confirmed in Japan, those are initial cases since 'swine-flu' was announced pandemic by WHO (World Health Organization). It is suggested, children and older people as well as patients of cardiac, renal and diabetes are more vulnerable to this flu (H1N1). It is a critical issue that this flu might have genetic mutations inside the body, thus brings more fatalities. Medical professionals in Bangladesh have much duties to prevent vast fatalities, due to densely populated region. There might be chance of getting 'vaccine' against this H1N1-flu in Japan at the end of this year. However, at present, it is wise to have mask in the crowded places and it is obviously necessary to wash hands and perform salt water gargle while come back home from outside. When body temp will rise up to 39 degree centigrade with somewhat muscle-ache, one must require to visit nearby hospital or clinic for check up. H1N1-flu induced fatalities must be prevented as it is already a pandemic around the world.

Perspectives of infection related brain disorders among children of developing countries.

Most of the developing countries around the world are densely populated with a higher child death rate, from different diseases. Infection-induced brain disorder is one of the delicate issues among child population of Bnagladesh too, which are caused by different microorganisms, mediated by environmental or immunological. There is a tendency to treat with antimicrobial agents or steroids after unwavering neuronal pathogenesis, either from bacterial, fungal or viral. Once neuronal pathogenesis is evolved, can be turned into fatal stage. Therefore, preventive measure is always essential to protect from fatal brain disorders. This should be taken into consideration, either genetic mutation of microorganisms can be transpired inside the body, due to environmental and/or other causes, the exact mechanism can not be revealed yet without much study data; however, it is of great essence to block evolving microorganisms across the blood brain barrier (BBB). Once this can be done, many fatalities can be prevented from neuronal disorders, and eventually child death rates will be lessened due to infection related brain disorders. Medical education among parents of child population especially in the rural areas may be one choice on this issue of prevention.

A report on ‘paracetamol-induced’ child death in Bangladesh!

I feel to analyze one report, published on ‘The daily Ittefaq’ on 23rd July issue, 2009, demonstrating deaths of twenty-three children in Bangladesh after intake of ‘paracetamol syrup’. Doctors in Bangladesh found that those ‘paracetamol syrup’ (brand name was not given) contained toxic chemicals (Ethylene and diethylene glycol) mixed up during manufacturing, which stimulated acute renal failure and terminated the lives of children. It is always heartbreaking news for us, the deaths of children either from natural or unnatural. The most disgusting and intolerable issue relating with drug-induced child death, should not be accepted in this modern civilization around the world when medical science is more advanced to augment the lifespan of humans. It is also not endurable when the cause of death is ‘drug’ (medicine), because drugs save lives from diseases. I personally feel, it is the time to open up mentality from pursuing most awful deeds, that instigating fatalities of humans such as children and/or adults in this modern civilization.