Sunday, August 22, 2010

Brain hemodynamic imbalance and antihypertensive drug!

Drugs have therapeutic effects and as well they also have side effects. However, most of the drugs do not show their adverse effects strongly. It is observed that some important drugs sued
in the major clinical disorder, have sometime major side effects. For this purpose, I would mention, one important anti-hypertensive drug (nifedipine) has adverse effect on global cerebral (brain) blood flow. One case study using nuclear medicine technique (SPECT scan) revealed that administartion of anti-hypertensive drug, nifedipine among hypertensive patients initiated inhomogenous global cerebral blood flow; however, cogntive impairment was not suggestive. It is suggested to pursue a close observation of hypertensive patients during antihypertensive drug administration.

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