Peculiar behavior of cancer cell!

Cancer cell has peculiar characteristic refer to destructive biological function. What we acknowledge that cancer cell has enormous arterial network that it generates it’s aggressiveness rapidly. However, recent concept reveals that some cancer cell is fully anoxic which is grown in the oxygen-deprived environment. These cancer cells usually are resistance to chemotherapy or radiotherapy. This is also a tough job for radiologist/oncoradiologist for final diagnostic interpretation. Then, we ought to maintain an oxygen containing environment against devastating cancer cell.

Myth or Fact!

Till scientists, doctors, health workers and social workers are running long hundred miles to fight against cancer. And until now, we are still on the way to discover the real biology of cancer. There are many predisposing factors such as environmental, behavioral, autonomous etc., those we know more or less and/or idiopathic. However, it is not a myth but fact that our own cell inside the body betrays in a certain stage to grow abnormal cell – referring to devastating ‘cancer’.

Antiviral medication – a role in the young population!

Tamiflu (brand-name) – a common antiviral medication is used against influenza virus (usually against H1N1). It has already been studied that this antiviral medication has adverse effect in the central nervous system, especially in the brain. There may be psychiatric symptom such as depression is common. Both adult and young people may have adverse effects from this drug administration. Recently one study in Japan using positron emission tomography (PET) imaging method showed that young people may have more adverse effects (i.e., depression like symptom) than the older people. So, dose-maintenance and specific observation are obligatory to prevent from any depression like symptom.

Central Brain Function AND Psychology.

Brain is the central regulator of physiological function of humans. It is acknowledged that chemical substances synthesized from the brain cells pursue specific physiological activities. Human psychology is a complicated phenomenon, which is regulated by the central brain function. There are some specific chemical substances produced by the brain cells, relating with the psychological status of human. It has already been studied that neuropsychological disorders such as schizophrenia, bipolar disorders (depression like disorder) etc. are linked with abnormal synthesis of certain chemical substance in the brain. Recently, functional imaging technique, positron emission tomography is useful to investigate psychological status of humans.

Winter flu and precautions!

Low temperature is always succeptible to flu infection. Usually temperature below 10 degree celsius is a suitable circumstance to catch a cold among humans. Children mostly suffer from influenza virus, which is critical for 'lung pneumonia'. In Japan, norovirus, a type of RNA virus is common flu-induced problem among children. Norovirus has also gastrointestinal symptom. The geriatric population (older population) are also victims of these viral infections during winter season, who mostly suffer from lung pneumonia, referring severe cardiorespiratory problem. Sometime this flu-induced infection among children and geriatric population become fatal. Therefore, precaution should be taken to keep body temperature increased. In addition, washing hands and rinsing mouths (gargle) are suggested after returning back home.

Is personality a factor for heart disease!

It is already acknowledged that personality has been related with development of heart disease by blocking artery of heart. Then, we look for personality which is harmful for our heart. It is suggested that people with type-A personality are susceptible to grow heart disease. People with type-A personality have more sympathetic outflow from autonomic nervous system, that eventually inducing excessive fat deposition on the cardiac arterial wall, developing blockage of cardiac artery. Sometime, social environment may aggravate behavioral anxiety, initiating aggressive personality in exuding excessive sympathetic flow. 'Self-meditation' such as deep breathing relaxation may be useful in abstaining from personality relating heart disease.

Importance of Brain Scan in Seizure: A Perspective!

The unintentional jerking of body (involuntary) is termed as seizure in medicine. The symptom of seizure has significant importance during clinical evaluation of a patient. For example, one young adult person may have seizure without other abnormality, so whole-brain scan should be additional investigation for clinical interpretation. With this perspective, childhood trauma of brain can not be ruled out as one cause, that can be assessed by brain imaging technique. Usually, CT and MRI are useful imaging techniques. Therefore, nowadays, advanced nuclear medicine technique such as Positron Emission Tomography (PET) imaging has also significant role in the functional and anatomical assessment among seizure patients with childhood brain trauma.

Benefits of Tomato against cancer!

For last few days, I am thinking to write about the beneficial effects of ‘tomato’, a seasonal fruit. There is a mixed impression on this fruit (tomato) relating with the taste. I myself use to take it as salad. However, the benefit of ingredient of tomato is little known to us, which is called lycopene, a carotenoid pigment usually found in the red and yellow fruits and vegetables. It has been studied that lycopene has anti-oxidant effect, that may prevent abnormal growth of cells in the body. I would like to mention that this lycopene has anti-cancer affect. It is studied that lycopene in the tomato may prevent prostate cancer in the middle decade of life. In addition, it has been postulated that lycopene has also anti-oxidant effect against breast cancer. Why do not we take tomato in our daily recipe? For any inconvenient taste of tomato, it can be taken as ketchup with our daily meal, I suggest.

Non-therapeutic approach: a benefit for psychological health!

Psychological symptom may be pronounced at any stage of life. Advanced technology such as nuclear medicine imaging method (positron emission tomography) has already stated that some neurotransmitters (chemical substances in the brain) have vast role in controlling human psychological status, synchronizing the brain and mind (emotion). Therefore, it is acknowledged that the emotion is mostly influenced by the higher brain function. There is therapeutic option (psychiatric medication) to prevent this psychological disorder in the medical procedure. However, some non-therapeutic approaches may have beneficial effects on higher brain function for modulating psychological symptoms. Body mind training (BMT) such as ‘deep breathing exercise’ is one useful non-therapeutic approach for psychological disorder, I suggest.

Hypertension and Lacunar stroke!

I would like to focus on hypertension-inducing brain stroke. There is always a chance of initiating brain stroke, suffering from malignant hypertension (MHTN). In the chronic stage (MHTN), there might be infarction of deep-brain structures, which is called lacunar stroke. Usually, deep structures of the brain are mostly involved in lacunar stroke, which is caused by the blockage of small arteries of deep brain.
Once this lacunar stroke is developed, it might be symptomless or mild symptoms are pronounced such as mild loss of sensation in the face, limbs or other parts of the body (sensory symptoms). MRI imaging method is useful to find out the lacunar stroke related deep brain lesions among the patients suffering from MHTN. However, it is useful to control chronic hypertension (MHTN) to prevent from lacular stroke.

Symptomless disease!

I desire to write about one devastating pathogenesis of major artery of human – carotid artery stenosis. I use to mention this stenosis carotid artery as carotid artery disease (CAD). The most devastating feature relating with clinical symptom is that this carotid artery stenosis sometime reveals symptomless, which is harmful for developing cerebral ischaemia. If we consider about medical problems that persuading carotid artery stenosis, cardiac disease (CD) or hypertension (HTN) are mentioned. Therefore, in regular medical check up of CD or HTN, it is wise to arrange one bed side examination of carotid arteries using US imaging method (ultrasound imaging).

Predictor of peripheral arterial disease and peripheral neuropathy!

A thorough clinical examination will pursue correct clinical diagnosis. With this perspective, I would mention two diseases - peripheral arterial disease (PAD) and peripheral neuropathy (PN). Peripheral arterial disease is caused due to peripheral arterial occlusion. The most common precipitating factor is atherosclerosis deriving from diabetes, hyperlipidaemia etc. In addition, Peripheral neuropathy is casued by infection related diseases (e.g., viral). Sometime it is a critical issue to assertain the specific physical symptoms of these two diseases - PAD and PN. Assessment of peripheral pulse should be a useful predictor for differentiate PAD and PN diseases.

Self-assessment can be fruitful!

Self-assessment can be a useful procedure in preventing some medical problems. For example, selft-assessment of any surface organ can detect any lump or sweling. We do not have to take these lump or swelling simple sometime. It is always a tendency to omit such lesions. Therefore, it is obligatory to assess the overall characteristics of those lesions in any surface organ of the body - size, shape, consistency are important to assess. For any abnormal score from self-assessment, it is wise to visit doctor for further medical procedures. Usuallay, beyond the 4th decade of life is delicate to grow any medical problem. So, self-assessment should be useful and fruitful, that I suggest.

Gingivitis (periodontal disease) can be fatal!

Gingivitis, a periodontal disease can be fatal in the course of pathogenesis. Sometime, we omit this gingivitis and we take it as a minor medical problem. First, I would like to reveal - what is gingivitis? The gingivitis is the infection of gum of tooth, caused by bacteria in general. When infection spreads upto 3mm or more than 3mm depth of gum, gingivitis is commenced. Now, the worst complications of this disease are heart disease or stroke. Recently, clinical study suggested that blood glucose concentration was increased in the patient, suffered from gingivitis, which is referred to gingivitis related diabetes. Therefore, precaution is to be taken to prevent from gingivitis inducing major medical problems such as heart disease or stroke. 'Dental hygene' is suggested.

Urinary urgency should not be neglected!

A mild medical symptom can be fatal and life-threatening. It is neglected as well. With this view point, I would mention 'urinary urgency' of male individual. It is postulated that some male subjects suggests urinary urgency (intermittent void) at night. Sometime, this persuades wake up at mid-night. This symptom sometime is avoided by someone, who suffers from it. He feels it as normal physiological process; however, this may be fatal and/or life threatening. This should be taken into medical symptom among middle-aged males. Medical check up is suggested for evaluate any abnormal genito-urinary function. Medical assessment of prostate is an appropriate choice with imaging evaluation and PSA assay, to arrange a 'timely medical management'.

Snoring can be a fatal medical problem!

Snoring is a physiological disorder that we often omit. It is always taken as less important physical problem; however, recently, it is studied that this snoring can be fatal medical problem. It is studied that elderly individual suffering from snoring may have absent respiration (apnea) for few
seconds during sleep. Then, intermittent snoring would aggravate cardiac related symptoms. Obesity is a significant cause of snoring among different age group. In another, elderly people suffer from snoring due to aging process. Therefore, physiological rehabilitation would be an important
non-therapeutic management of snoring for different age group individual as to prevent from it. Deep voice training is suggested, revealing useful physiological rehabilitation.

Benefit of dark chocolate!

Chocolate is a delicious food that my daughter always presses me to buy for her. However, this chocolate has greater beneficial effects on cardiovascular health. It is suggested that one bit of dark chocolate per week may reduce the risk of heart disease (risk of heart failure) [source: Journal of Circulation]. The mechanism is not clear enough; however, it is investigated that flavonoid ingedient in the cocoa acts on blood vessel and reduces the blood pressure. Therefore, it is wise to maintain a normal blood pressure as to prevent from heart diseases.

Brain hemodynamic imbalance and antihypertensive drug!

Drugs have therapeutic effects and as well they also have side effects. However, most of the drugs do not show their adverse effects strongly. It is observed that some important drugs sued
in the major clinical disorder, have sometime major side effects. For this purpose, I would mention, one important anti-hypertensive drug (nifedipine) has adverse effect on global cerebral (brain) blood flow. One case study using nuclear medicine technique (SPECT scan) revealed that administartion of anti-hypertensive drug, nifedipine among hypertensive patients initiated inhomogenous global cerebral blood flow; however, cogntive impairment was not suggestive. It is suggested to pursue a close observation of hypertensive patients during antihypertensive drug administration.

Significance of physical therapy in low back pain!

It is always a common problem from eraly middle age - low back pain. This low back pain usually is commenced at early morning. It is presuamably assumed that early morning back pain is related with temperature and/or hormonal balance. Physicians usually suggest normal pelvic X-ray, however, MRI scanning is useful in evaluating any disk prolapse. Spinal stenosis should be important cause of this low back pain - persuaded by degeneration or trauma. In this case, I always prefer proper clinical history, that would be important for appropriate investigation and management. Usually, symptomatic treatment with vitamin supplements are suggested (vitamin D or Vitamin B1). Rehabilitation is an important non-therapeutic management in low back pain - aerobic training (ergometer bicycle pedal) in flexed position (40 to 50 min for 4 to 5 days) are suggested by considering patients' condition.

How to preserve normal I.Q.!

Always I have a tendency to be clever, though I am not at all. From my childhood, I was always poor in I.Q. (Intelligence quotient); however, nowadays I try to elucidate to retain it in natural phenomenon. Our brain has complex network of neurons (brain cell) those are responsible for keeping a smart I.Q. Usually normal I.Q. should be 100 for a human. However, mentally retarded people (congenital neurodegeneration) have sometime less than 25 of I.Q., those who need full time care by family and/or by nursing home. For a normal human, after the middle age (after 40 y.o.), some natural degeneration of neurons are commenced that initiating some aberrant neuronal networking in the brain refer to decrease in I.Q. Now, it is to evaluate to retain the I.Q. after the middle age – the physical exercise, cognitive training, balanced nutrition etc. are useful natural approaches.