Thursday, September 24, 2009

Mystery of swine-flu (H1N1): an update.

Swine flu (H1N1 virus) has aggressive effects on humans due to its rapid replication. Though swine-flu attacks the lung parenchyma in the early phase of inflammation initiating severe lung pneumonia, recently it is studied that other vital organs (liver, kidney and brain) are brutally affected, showing its fatality. It is investigated that in the pathogenesis step inside the body, this influenza virus (swine-flu, H1N1) encourages discharge of inflammatory cytokines,
immunomodulating agents. Therefore, these inflammatory cytokines hinder liver and kidney function in the pathogenesis. Another harmful complication of swine-flu (H1N1) is, damaging of brain cells (neurons), those demonstrate irreversible. So, it is recommended to start antiflu drugs (Tamiflu or Relenza) as soon as possible with physician's prescription after H1N1 is diagnosed. It is recommended, to take temperature records regularly for the baby-care center or school-gloing children in the epidemic regions.

Thursday, September 10, 2009

Is gastric ulcer linked with diabetes?

Insulin resistance diabetes is a common problem around all over the world, mainly originating from obesity due to overeating and sedentary lifestyle. Hyperglycemia is always susceptible to enhance other pathogenesis such a diabetic ulcer, angiopathy, neuropathy etc. Recently, a group of medical scientists in Japan (Tohoku University, my host University) found that one insulin resistance diabetic patient was completely recovered when treated with pylori healing antibiotic, which was published in July 18 edition of The Lancet British medical journal. The mechanism of developing insulin resistance diabetes among pylori-induced ulcer patients is not clear enough; however, there might be some autoimmune effects. We need to find out the specific immune response against insulin that causes diabetes. In another, it is not known yet whether hyperglycemia may have influence on H. pylori growth in the stomach mucosa. Therefore, it is important to treat pylori-induced stomach ulcer first in insulin-resistant diabetic patient to cure diabetes.